BECKER MUSCULAR DYSTROPHY
\bˈɛkə mˈʌskjʊlə dˈɪstɹəfi], \bˈɛkə mˈʌskjʊlə dˈɪstɹəfi], \b_ˈɛ_k_ə m_ˈʌ_s_k_j_ʊ_l_ə d_ˈɪ_s_t_ɹ_ə_f_i]\
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a form of muscular dystrophy that set in in adolescence or adulthood and progresses slowly but will affect all voluntary muscles; characterized by generalized weakness and muscle wasting that affects limb and trunk muscles first.
By Princeton University
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An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
By DataStellar Co., Ltd
Word of the day
hydromorphic
- [Greek] Structurally adapted to an aquatic environment, as organs of water plants.