ARYLSULFATASE B1
\ˈɑːɹɪlsˌʌlfɐtˌe͡ɪs bˈiː wˈɒn], \ˈɑːɹɪlsˌʌlfɐtˌeɪs bˈiː wˈɒn], \ˈɑː_ɹ_ɪ_l_s_ˌʌ_l_f_ɐ_t_ˌeɪ_s b_ˈiː w_ˈɒ_n]\
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An arylsulfatase that catalyzes the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate. A deficiency of this enzyme is responsible for the inherited lysosomal disease, Maroteaux-Lamy syndrome (MUCOPOLYSACCHARIDOSIS VI). EC 3.1.6.12.
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Word of the day
TMP
- 5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.