ANTIBODY AFFINITIES
\ˈantɪbˌɒdi ɐfˈɪnɪtiz], \ˈantɪbˌɒdi ɐfˈɪnɪtiz], \ˈa_n_t_ɪ_b_ˌɒ_d_i_ ɐ_f_ˈɪ_n_ɪ_t_i_z]\
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A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.
By DataStellar Co., Ltd
