AIDS ASSOCIATED NEPHROPATHY
\ˈe͡ɪdz ɐsˈə͡ʊsɪˌe͡ɪtɪd nɛfɹˈɒpəθɪ], \ˈeɪdz ɐsˈəʊsɪˌeɪtɪd nɛfɹˈɒpəθɪ], \ˈeɪ_d_z ɐ_s_ˈəʊ_s_ɪ__ˌeɪ_t_ɪ_d n_ɛ_f_ɹ_ˈɒ_p_ə_θ_ɪ]\
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Renal syndrome in human immunodeficiency virus-infected patients characterized by nephrotic syndrome, severe proteinuria, focal and segmental glomerulosclerosis with distinctive tubular and interstitial changes, enlarged kidneys, and peculiar tubuloreticular structures. The syndrome is distinct from heroin-associated nephropathy as well as other forms of kidney disease seen in HIV-infected patients.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.