AIDS ASSOCIATED LYMPHOMA
\ˈe͡ɪdz ɐsˈə͡ʊsɪˌe͡ɪtɪd lɪmfˈə͡ʊmə], \ˈeɪdz ɐsˈəʊsɪˌeɪtɪd lɪmfˈəʊmə], \ˈeɪ_d_z ɐ_s_ˈəʊ_s_ɪ__ˌeɪ_t_ɪ_d l_ɪ_m_f_ˈəʊ_m_ə]\
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B-cell lymphoid tumors that occur in association with AIDS. Patients often present with an advanced stage of disease and highly malignant subtypes including Burkitt lymphoma, immunoblastic large-cell lymphoma, small non-cleaved-cell lymphoma and diffuse large-cell lymphoma. The tumors are often disseminated in unusual extranodal sites and chromosomal abnormalities are frequently present. It is likely that polyclonal B-cell lymphoproliferation in AIDS is a complex result of EBV infection, HIV antigenic stimulation, and T-cell-dependent HIV activation.
By DataStellar Co., Ltd
