AE1 ANION EXCHANGER
\ˌe͡ɪˈiː wˈɒn ˈana͡ɪən ɛkst͡ʃˈe͡ɪnd͡ʒə], \ˌeɪˈiː wˈɒn ˈanaɪən ɛkstʃˈeɪndʒə], \ˌeɪ_ˈiː w_ˈɒ_n ˈa_n_aɪ_ə_n ɛ_k_s_tʃ_ˈeɪ_n_dʒ_ə]\
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A ubiquitous membrane transport protein found in the plasma membrane of diverse cell types and tissues, and in nuclear, mitochondrial, and Golgi membranes. It is the major integral transmembrane protein of the erythrocyte plasma membrane, comprising 25% of the total membrane protein. It exists as a dimer and performs the important function of allowing the efficient transport of bicarbonate across erythrocyte cell membranes in exchange for chloride ion.
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