ADRENERGIC ALPHA 2 RECEPTORS
\ɐdɹɪnˈɜːd͡ʒɪk ˈalfə tˈuː ɹɪsˈɛptəz], \ɐdɹɪnˈɜːdʒɪk ˈalfə tˈuː ɹɪsˈɛptəz], \ɐ_d_ɹ_ɪ_n_ˈɜː_dʒ_ɪ_k ˈa_l_f_ə t_ˈuː ɹ_ɪ_s_ˈɛ_p_t_ə_z]\
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A subclass of alpha-adrenergic receptors (RECEPTORS, ADRENERGIC, ALPHA). alpha-2 Adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist clonidine and the antagonist yohimbine. They are found on pancreatic beta cells, platelets, and vascular smooth muscle, as well as both pre- and postsynaptically in the central and peripheral nervous systems.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.