5,8,11,14,17 ICOSAPENTAENOIC ACID
\fˈa͡ɪv ˈe͡ɪt ɪlˈɛvən fˈɔːtiːn sˈɛvəntˌiːn ˈa͡ɪkəsˌe͡ɪpəntˌiːnə͡ʊɪk ˈasɪd], \fˈaɪv ˈeɪt ɪlˈɛvən fˈɔːtiːn sˈɛvəntˌiːn ˈaɪkəsˌeɪpəntˌiːnəʊɪk ˈasɪd], \f_ˈaɪ_v ˈeɪ_t ɪ_l_ˈɛ_v_ə_n f_ˈɔː_t_iː_n s_ˈɛ_v_ə_n_t_ˌiː_n ˈaɪ_k_ə_s_ˌeɪ_p_ə_n_t_ˌiː_n_əʊ_ɪ_k ˈa_s_ɪ_d]\
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Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.