2589 R.B.
\tˈuː θˈa͡ʊzənd fˈa͡ɪvhˈʌndɹədən ˈe͡ɪtinˈa͡ɪn ˌɑːbˈiː], \tˈuː θˈaʊzənd fˈaɪvhˈʌndɹədən ˈeɪtinˈaɪn ˌɑːbˈiː], \t_ˈuː θ_ˈaʊ_z_ə_n_d f_ˈaɪ_v_h_ˈʌ_n_d_ɹ_ə_d_ə_n ˈeɪ_t_i_n_ˈaɪ_n ˌɑː_b_ˈiː]\
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Olivopontocerebellar Atrophies
- group inherited disorders which share progressive ataxia combination with atrophy CEREBELLUM; PONS; inferior olivary nuclei. Additional features include RIGIDITY; NYSTAGMUS; RETINAL DEGENERATION; MUSCLE SPASTICITY; DEMENTIA; URINARY INCONTINENCE; OPHTHALMOPLEGIA. familial has an earlier onset (second decade) and may feature spinal cord atrophy. sporadic form tends to present in the fifth or sixth decade, is considered a clinical subtype MULTIPLE SYSTEM ATROPHY. (From Adams et al., Principles of Neurology, 6th ed, p1085)