25 HYDROXYCHOLECALCIFEROL BINDING PROTEIN
\twˈɛntifˈa͡ɪv hˈa͡ɪdɹəksˌɪkə͡ʊlkˌalsɪfəɹˌɒl bˈa͡ɪndɪŋ pɹˈə͡ʊtiːn], \twˈɛntifˈaɪv hˈaɪdɹəksˌɪkəʊlkˌalsɪfəɹˌɒl bˈaɪndɪŋ pɹˈəʊtiːn], \t_w_ˈɛ_n_t_i_f_ˈaɪ_v h_ˈaɪ_d_ɹ_ə_k_s_ˌɪ_k_əʊ_l_k_ˌa_l_s_ɪ_f_ə_ɹ_ˌɒ_l b_ˈaɪ_n_d_ɪ_ŋ p_ɹ_ˈəʊ_t_iː_n]\
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An alpha-globulin found in the plasma of man and other vertebrates. It is apparently synthesized in the liver and carries vitamin D and its metabolites through the circulation and mediates the response of tissue. It is also known as group-specific component (Gc). Gc subtypes are used to determine specific phenotypes and gene frequencies. These data are employed in the classification of population groups, paternity investigations, and in forensic medicine.
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Harmar, Josiah
- (1753-1813), born in Philadelphia, served during Revolutionary War, attaining rank of lieutenant-colonel, and was commander-in-chief the U.S. army from 1789 to 1792.