1,7 DIHYDRO 6H PURINE 6 THIONE
\wˈɒn sˈɛvən da͡ɪhˈa͡ɪdɹə͡ʊ sˈɪks ˈe͡ɪt͡ʃ pjˈʊɹiːn sˈɪks θˌa͡ɪə͡ʊn], \wˈɒn sˈɛvən daɪhˈaɪdɹəʊ sˈɪks ˈeɪtʃ pjˈʊɹiːn sˈɪks θˌaɪəʊn], \w_ˈɒ_n s_ˈɛ_v_ə_n d_aɪ_h_ˈaɪ_d_ɹ_əʊ s_ˈɪ_k_s ˈeɪ_tʃ p_j_ˈʊ_ɹ_iː_n s_ˈɪ_k_s θ_ˌaɪ_əʊ_n]\
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An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.