XAMOTEROL HEMIFUMARATE
\zˈamə͡ʊtɹˌɒl hˈɛmɪfjˌuːmɐɹˌe͡ɪt], \zˈaməʊtɹˌɒl hˈɛmɪfjˌuːmɐɹˌeɪt], \z_ˈa_m_əʊ_t_ɹ_ˌɒ_l h_ˈɛ_m_ɪ_f_j_ˌuː_m_ɐ_ɹ_ˌeɪ_t]\
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A selective beta-1-adrenergic partial agonist. Because it is a partial agonist it acts like an agonist when sympathetic activity is low and as an antagonist when sympathetic activity is high. It reduces myocardial ischemia and improves ventricular function in patients with mild to moderate heart failure. In patients with severe heart failure it has been shown to produce benefits in systolic and diastolic function.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.