WEAKLY INTERACTING MASSIVE PARTICLE

\wˈiːkli ˌɪntəɹˈaktɪŋ mˈasɪv pˈɑːtɪkə͡l], \wˈiːkli ˌɪntəɹˈaktɪŋ mˈasɪv pˈɑːtɪkə‍l], \w_ˈiː_k_l_i_ ˌɪ_n_t_ə_ɹ_ˈa_k_t_ɪ_ŋ m_ˈa_s_ɪ_v p_ˈɑː_t_ɪ_k_əl]\

Definitions of WEAKLY INTERACTING MASSIVE PARTICLE

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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