V FMS ONCOGENE
\vˈiː ˌɛfˌɛmˈɛs ˈɒnkə͡ʊd͡ʒˌiːn], \vˈiː ˌɛfˌɛmˈɛs ˈɒnkəʊdʒˌiːn], \v_ˈiː_ ˌɛ_f_ˌɛ_m_ˈɛ_s ˈɒ_n_k_əʊ_dʒ_ˌiː_n]\
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Family of genes originally isolated from the Susan McDonough strain of feline sarcoma virus (SARCOMA VIRUSES, FELINE). The proto-oncogene fms (c-fms) codes for the MCSF receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR). The oncogene fms (v-fms) codes for ONCOGENE PROTEIN GP1409 (V-FMS) which is a mutated form of the MCSF. The human c-fms gene is located between 5q33.2 and 5q33.3.
By DataStellar Co., Ltd
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Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.