V SRC ONCOGENE
\vˈiː ˌɛsˌɑːsˈiː ˈɒnkə͡ʊd͡ʒˌiːn], \vˈiː ˌɛsˌɑːsˈiː ˈɒnkəʊdʒˌiːn], \v_ˈiː_ ˌɛ_s_ˌɑː_s_ˈiː_ ˈɒ_n_k_əʊ_dʒ_ˌiː_n]\
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Retrovirus-associated DNA sequences (src) originally isolated from the Rous sarcoma virus (RSV). The proto-oncogene src (c-src) codes for a protein that is a member of the tyrosine kinase family and was the first proto-oncogene identified in the human genome. The human c-src gene is located at 20q12-13 on the long arm of chromosome 20.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.