V REL PROTEINS
\vˈiː ɹˈɛl pɹˈə͡ʊtiːnz], \vˈiː ɹˈɛl pɹˈəʊtiːnz], \v_ˈiː ɹ_ˈɛ_l p_ɹ_ˈəʊ_t_iː_n_z]\
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Transforming proteins coded by rel oncogenes. The v-rel protein competes with rel-related proteins and probably transforms cells by acting as a dominant negative version of c-rel. This results in the induction of a broad range of leukemias and lymphomas.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.