V JUN GENES
\vˈiː d͡ʒˈʌn d͡ʒˈiːnz], \vˈiː dʒˈʌn dʒˈiːnz], \v_ˈiː dʒ_ˈʌ_n dʒ_ˈiː_n_z]\
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Retrovirus-associated DNA sequences (jun) originally isolated from the avian sarcoma virus 17 (ASV 17). The proto-oncogene jun (c-jun) codes for a nuclear protein which is involved in growth-related transcriptional control. Insertion of c-jun into ASV-17 or the constitutive expression of the c-jun protein produces tumorgenicity. The human c-jun gene is located at 1p31-32 on the short arm of chromosome 1.
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Word of the day
tinctura quininae ammoniata
- A preparation made by dissolving quinin sulphate in alcohol [Br. Ph.].