Uptown \Up*town"\, adv. To or in the upper part of a town; as, to go uptown. [Colloq. U. S.]
Source: Webster's Revised Unabridged Dictionary (1913)
Uptown \Up"town`\, a. Situated in, or belonging to, the upper part of a town or city; as, a uptown street, shop, etc.; uptown society. [Colloq. U. S.]