UPRIGHTLY
\ˈʌpɹa͡ɪtli], \ˈʌpɹaɪtli], \ˈʌ_p_ɹ_aɪ_t_l_i]\
Definitions of UPRIGHTLY
- 2006 - WordNet 3.0
- 2011 - English Dictionary Database
- 1871 - The Cabinet Dictionary of the English Language
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ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.