UNFAITHFULNESS
\ʌnfˈe͡ɪθfə͡lnəs], \ʌnfˈeɪθfəlnəs], \ʌ_n_f_ˈeɪ_θ_f_əl_n_ə_s]\
Definitions of UNFAITHFULNESS
- 1874 - Etymological and pronouncing dictionary of the English language
- 1871 - The Cabinet Dictionary of the English Language
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By Stormonth, James, Phelp, P. H.
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ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.