UNDIFFERENTIATED LYMPHOMAS
\ʌndˌɪfəɹˈɛnʃɪˌe͡ɪtɪd lɪmfˈə͡ʊməz], \ʌndˌɪfəɹˈɛnʃɪˌeɪtɪd lɪmfˈəʊməz], \ʌ_n_d_ˌɪ_f_ə_ɹ_ˈɛ_n_ʃ_ɪ__ˌeɪ_t_ɪ_d l_ɪ_m_f_ˈəʊ_m_ə_z]\
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A form of lymphoma in which relatively large stem cells with large nuclei, pale, scanty cytoplasm, and indistinct borders are predominant. The cells are undifferentiated, i.e., show no morphologic evidence of maturation toward lymphocytes or histiocytes.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.