UMBILICAL CORD BLOODS
\ʌmbˈɪlɪkə͡l kˈɔːd blˈʌdz], \ʌmbˈɪlɪkəl kˈɔːd blˈʌdz], \ʌ_m_b_ˈɪ_l_ɪ_k_əl k_ˈɔː_d b_l_ˈʌ_d_z]\
Word of the day
ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.