UDP GLUCURONYL TRANSFERASE
\jˌuːdˌiːpˈiː ɡlˈuːkjʊɹˌɒna͡ɪl tɹansfˈɜːɹe͡ɪz], \jˌuːdˌiːpˈiː ɡlˈuːkjʊɹˌɒnaɪl tɹansfˈɜːɹeɪz], \j_ˌuː_d_ˌiː_p_ˈiː ɡ_l_ˈuː_k_j_ʊ_ɹ_ˌɒ_n_aɪ_l t_ɹ_a_n_s_f_ˈɜː_ɹ_eɪ_z]\
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A family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing enzymes that catalyze the conjugation of UDPglucuronic acid to a variety of endogenous and exogenous compounds. EC 2.4.1.17.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.