UBIQUITIN
\jˈuːbɪkwˌɪtɪn], \jˈuːbɪkwˌɪtɪn], \j_ˈuː_b_ɪ_k_w_ˌɪ_t_ɪ_n]\
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A highly conserved 76-amino acid peptide universally found in eukaryotic cells that functions as a marker for intracellular PROTEIN TRANSPORT and degradation. Ubiquitin becomes activated through a series of complicated steps and forms an isopeptide bond to lysine residues of specific proteins within the cell. These "ubiquitinated" proteins can be recognized and degraded by proteosomes or be transported to specific compartments within the cell.
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Word of the day
tinctura quininae ammoniata
- A preparation made by dissolving quinin sulphate in alcohol [Br. Ph.].