TUMOR AUTOCRINE MOTILITY FACTOR
\tjˈuːməɹ ˌɔːtə͡ʊkɹˈa͡ɪn mə͡ʊtˈɪlɪti fˈaktə], \tjˈuːməɹ ˌɔːtəʊkɹˈaɪn məʊtˈɪlɪti fˈaktə], \t_j_ˈuː_m_ə_ɹ ˌɔː_t_əʊ_k_ɹ_ˈaɪ_n m_əʊ_t_ˈɪ_l_ɪ_t_i f_ˈa_k_t_ə]\
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A member of the class of cytokines secreted by tumor cells. It elicits increases in cell motility and phosphoinositide metabolism in the secreting or producing cell via a pertussis toxin-sensitive G-protein signal transduction pathway. The factor has also been used as a marker for bladder cancer.
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.