TRIGEMINAL NEUROPATHIES
\tɹa͡ɪd͡ʒˈɛmɪnə͡l njuːɹˈɒpəθɪz], \tɹaɪdʒˈɛmɪnəl njuːɹˈɒpəθɪz], \t_ɹ_aɪ_dʒ_ˈɛ_m_ɪ_n_əl n_j_uː_ɹ_ˈɒ_p_ə_θ_ɪ_z]\
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Diseases of the trigeminal nerve or its nuclei, which are located in the pons and medulla. The nerve is composed of three divisions: ophthalmic, maxillary, and mandibular, which provide sensory innervation to structures of the face, sinuses, and portions of the cranial vault. The mandibular nerve also innervates muscles of mastication. Clinical features include loss of facial and intra-oral sensation and weakness of jaw closure. Common conditions affecting the nerve include brain stem ischemia, INFRATENTORIAL NEOPLASMS, and TRIGEMINAL NEURALGIA.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.