TRANSLOCATION (GENETICS)
\tɹanslə͡ʊkˈe͡ɪʃən d͡ʒɛnˈɛtɪks], \tɹansləʊkˈeɪʃən dʒɛnˈɛtɪks], \t_ɹ_a_n_s_l_əʊ_k_ˈeɪ_ʃ_ə_n__ dʒ_ɛ_n_ˈɛ_t_ɪ_k_s]\
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A type of aberration characterized by fragmentation of a chromosome and transfer of the broken-off portion to another chromosome, often of a different pair.
By DataStellar Co., Ltd
Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.