TRANSFORMING GENE
\tɹansfˈɔːmɪŋ d͡ʒˈiːn], \tɹansfˈɔːmɪŋ dʒˈiːn], \t_ɹ_a_n_s_f_ˈɔː_m_ɪ_ŋ dʒ_ˈiː_n]\
Definitions of TRANSFORMING GENE
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By Princeton University
By DataStellar Co., Ltd
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Genes which can potentially induce neoplastic transformation. They include genes for growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. When these genes are constitutively expressed after structural and/or regulatory changes, uncontrolled cell proliferation may result. Viral oncogenes have prefix "v-" before the gene symbol; cellular oncogenes (PROTO-ONCOGENES) have the prefix "c-" before the gene symbol.
By DataStellar Co., Ltd
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