TOXIC GASTRI'TIS

\tˈɒksɪk ɡˈastɹɪtˌiz], \tˈɒksɪk ɡˈastɹɪtˌiz], \t_ˈɒ_k_s_ɪ_k ɡ_ˈa_s_t_ɹ_ɪ_t_ˌi_z]\

Definitions of TOXIC GASTRI'TIS

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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