TOPOISOMERASE II
\tˈɒpɔ͡ɪsˌə͡ʊmɹe͡ɪz ɹˌə͡ʊmən tˈuː], \tˈɒpɔɪsˌəʊmɹeɪz ɹˌəʊmən tˈuː], \t_ˈɒ_p_ɔɪ_s_ˌəʊ_m_ɹ_eɪ_z ɹ_ˌəʊ_m_ə_n_ t_ˈuː]\
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DNA TOPOISOMERASES that catalyze ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. These enzymes bring about relaxation of the supercoiled DNA and resolution of a knotted circular DNA duplex.
By DataStellar Co., Ltd
