TOO BIG FOR ONE'S BREECHES

\tˈuː bˈɪɡ fɔː wˈɒnz bɹˈiːt͡ʃɪz], \tˈuː bˈɪɡ fɔː wˈɒnz bɹˈiːt‍ʃɪz], \t_ˈuː b_ˈɪ_ɡ f_ɔː w_ˈɒ_n_z b_ɹ_ˈiː_tʃ_ɪ_z]\

Definitions of TOO BIG FOR ONE'S BREECHES

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2006 - WordNet 3.0
By Princeton University
 
2011 - English Dictionary Database
By DataStellar Co., Ltd

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Proto Oncogene Proteins c erbB 2

  • cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
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