TONNAGE AND POUNDAGE

\tˈʌnɪd͡ʒ and pˈa͡ʊndɪd͡ʒ], \tˈʌnɪd‍ʒ and pˈa‍ʊndɪd‍ʒ], \t_ˈʌ_n_ɪ_dʒ a_n_d p_ˈaʊ_n_d_ɪ_dʒ]\

Definitions of TONNAGE AND POUNDAGE

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1895 - Glossary of terms and phrases
By Henry Percy Smith

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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