THROMBOPLASTINOGEN
\θɹˈɒmbəplˌastɪnəd͡ʒən], \θɹˈɒmbəplˌastɪnədʒən], \θ_ɹ_ˈɒ_m_b_ə_p_l_ˌa_s_t_ɪ_n_ə_dʒ_ə_n]\
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Blood-coagulation factor VIII. Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.