THREONINE DEHYDRASE
\θɹɪˈɒna͡ɪn dˌiːha͡ɪdɹˈe͡ɪz], \θɹɪˈɒnaɪn dˌiːhaɪdɹˈeɪz], \θ_ɹ_ɪ__ˈɒ_n_aɪ_n d_ˌiː_h_aɪ_d_ɹ_ˈeɪ_z]\
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A pyridoxal-phosphate protein that catalyzes the deamination of threonine to 2-ketobutyrate and ammonia. The role of this enzyme can be biosynthetic or biodegradative. In the former role it supplies 2-ketobutyrate required for isoleucine biosynthesis, while in the latter it is only involved in the breakdown of threonine to supply energy. EC 4.2.1.16.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.