THOST UNNA SYNDROME
\θˈə͡ʊst ʌnnˈa sˈɪndɹə͡ʊm], \θˈəʊst ʌnnˈa sˈɪndɹəʊm], \θ_ˈəʊ_s_t ʌ_n_n_ˈa s_ˈɪ_n_d_ɹ_əʊ_m]\
Definitions of THOST UNNA SYNDROME
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An autosomal dominant disorder characterized by a widely distributed, well-demarcated hyperkeratosis of the palms and soles. There is more than one genotypically distinct form, each of which is clinically similar but histologically distinguishable. Diffuse palmoplantar keratoderma is distinct from palmoplantar keratoderma (KERATODERMA, PALMOPLANTAR), as the former exhibits autosomal dominant inheritance and hyperhidrosis is frequently present.
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