\tˌɛlɪˌɒspɔːɹˈɪfəɹəs], \tˌɛlɪˌɒspɔːɹˈɪfəɹəs], \t_ˌɛ_l_ɪ__ˌɒ_s_p_ɔː_ɹ_ˈɪ_f_ə_ɹ_ə_s]\


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  • Teleutosporiferous.
1920 - A dictionary of scientific terms.
By Henderson, I. F.; Henderson, W. D.

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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