\tɔːˈɒpəθɪz], \tɔːˈɒpəθɪz], \t_ɔː_ˈɒ_p_ə_θ_ɪ_z]\
Definitions of TAUOPATHIES
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Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE, DEMENTIA, PARKINSONIAN DISORDERS, progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE), and corticobasal degeneration.
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