TAPIA'S SYNDROME

\tˈe͡ɪpiəz sˈɪndɹə͡ʊm], \tˈe‍ɪpiəz sˈɪndɹə‍ʊm], \t_ˈeɪ_p_i__ə_z s_ˈɪ_n_d_ɹ_əʊ_m]\

Definitions of TAPIA'S SYNDROME

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1920 - A practical medical dictionary.
By Stedman, Thomas Lathrop

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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