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Definitions of T3 Antigen

  1. Complex of at least five membrane- bound polypeptides in mature T- lymphocytes that are non- covalently associated with one another and with the T- cell receptor ( RECEPTORS, ANTIGEN, T- CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains ( subunits). When antigen binds to the T- cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T- cell. The CD3 gamma and delta chains ( subunits) are separate from and not related to the gamma/ delta chains of the T- cell receptor ( RECEPTORS, ANTIGEN, T- CELL, GAMMA- DELTA).
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