T CELL RECEPTORS GAMMA CHAIN
\tˈiː sˈɛl ɹɪsˈɛptəz ɡˈamə t͡ʃˈe͡ɪn], \tˈiː sˈɛl ɹɪsˈɛptəz ɡˈamə tʃˈeɪn], \t_ˈiː s_ˈɛ_l ɹ_ɪ_s_ˈɛ_p_t_ə_z ɡ_ˈa_m_ə tʃ_ˈeɪ_n]\
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T-cell receptors composed of CD3-associated gamma and delta polypeptide chains and expressed primarily in CD4-/CD8- T-cells. The receptors appear to be preferentially located in epithelial sites and probably play a role in the recognition of bacterial antigens. The T-cell receptor gamma/delta chains are separate and not related to the gamma and delta chains which are subunits of CD3 (see ANTIGENS, CD3).
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.