T CELL RECEPTOR ALPHA CHAIN
\tˈiː sˈɛl ɹɪsˈɛptəɹ ˈalfə t͡ʃˈe͡ɪn], \tˈiː sˈɛl ɹɪsˈɛptəɹ ˈalfə tʃˈeɪn], \t_ˈiː s_ˈɛ_l ɹ_ɪ_s_ˈɛ_p_t_ə_ɹ ˈa_l_f_ə tʃ_ˈeɪ_n]\
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T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primarily in CD4+ or CD8+ T-cells. Unlike immunoglobulins, the alpha-beta T-cell receptors recognize antigens only when presented in association with major histocompatibility (MHC) molecules.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.