T CELL GROWTH FACTOR RECEPTORS
\tˈiː sˈɛl ɡɹˈə͡ʊθ fˈaktə ɹɪsˈɛptəz], \tˈiː sˈɛl ɡɹˈəʊθ fˈaktə ɹɪsˈɛptəz], \t_ˈiː s_ˈɛ_l ɡ_ɹ_ˈəʊ_θ f_ˈa_k_t_ə ɹ_ɪ_s_ˈɛ_p_t_ə_z]\
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Receptors present on activated T- and B-cells as a complex consisting of a 55 kD peptide, which reacts with the anti-Tac monoclonal antibody, and a 75 kD non-Tac interleukin-2-binding peptide. The receptor is present in two forms, one with a very high affinity and the other with low affinity for IL-2. The high-affinity form appears to mediate exclusively the growth-promoting response to IL-2. The receptor is present in large numbers on resting HUMAN T-LYMPHOTROPIC VIRUS 1 leukemia cells, but not on normal resting cells.
By DataStellar Co., Ltd
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Nearby Words
- t cell gene rearrangements
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- t cell growth factor
- t cell growth factor p40
- t cell growth factor receptor
- T Cell Growth Factor Receptors
- t cell homing receptors
- t cell leukemia
- t cell leukemia lymphoma virus antibodies, human
- t cell leukemia lymphoma virus antigens, human
- t cell leukemia lymphoma, adult