SYMPTOMATIC INFANTILE SPASM
\sˌɪmptəmˈatɪk ˈɪnfəntˌa͡ɪl spˈazəm], \sˌɪmptəmˈatɪk ˈɪnfəntˌaɪl spˈazəm], \s_ˌɪ_m_p_t_ə_m_ˈa_t_ɪ_k ˈɪ_n_f_ə_n_t_ˌaɪ_l s_p_ˈa_z_ə_m]\
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An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
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