SWINE EXUDATIVE DERMATITIDES
\swˈa͡ɪn ɛɡzjˈuːdətˌɪv dˈɜːmɐtˌɪta͡ɪdz], \swˈaɪn ɛɡzjˈuːdətˌɪv dˈɜːmɐtˌɪtaɪdz], \s_w_ˈaɪ_n ɛ_ɡ_z_j_ˈuː_d_ə_t_ˌɪ_v d_ˈɜː_m_ɐ_t_ˌɪ_t_aɪ_d_z]\
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An acute generalized dermatitis of pigs which occurs from 5 to 35 days of age, characterized by sudden onset, with morbidity of 10 to 90% and mortality of 5 to 90%. The lesions are caused by Staphylococcus hyos but the bacterial agent is unable to penetrate the intact skin. Abrasions on the feet and legs or lacerations on the body frequently precede infection. In acute cases, a vesicular-type virus may be the predisposing factor. The causative organism is inhibited by most antibiotics. (Merck Veterinary Manual, 5th ed)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.