\sˈʌɹəɡˌe͡ɪt mˈɑːkə], \sˈʌɹəɡˌeɪt mˈɑːkə], \s_ˈʌ_ɹ_ə_ɡ_ˌeɪ_t m_ˈɑː_k_ə]\
Definitions of SURROGATE MARKER
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Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
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