SUBSEPSIS ALLERGICA
\sʌbsˈɛpsɪs ˈaləd͡ʒˌɪkə], \sʌbsˈɛpsɪs ˈalədʒˌɪkə], \s_ʌ_b_s_ˈɛ_p_s_ɪ_s ˈa_l_ə_dʒ_ˌɪ_k_ə]\
Word of the day
ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.