\sˈʌblɪɡˌe͡ɪmɛn], \sˈʌblɪɡˌe‍ɪmɛn], \s_ˈʌ_b_l_ɪ_ɡ_ˌeɪ_m_ɛ_n]\
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1898 - Warner's pocket medical dictionary of today.
By William R. Warner

Word of the day

ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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