STRIATONIGRAL DEGENERATIONS
\stɹˈa͡ɪɐtˌɒnɪɡɹə͡l dɪd͡ʒˌɛnəɹˈe͡ɪʃənz], \stɹˈaɪɐtˌɒnɪɡɹəl dɪdʒˌɛnəɹˈeɪʃənz], \s_t_ɹ_ˈaɪ__ɐ_t_ˌɒ_n_ɪ_ɡ_ɹ_əl d_ɪ_dʒ_ˌɛ_n_ə_ɹ_ˈeɪ_ʃ_ə_n_z]\
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A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsonian features (e.g., MUSCLE RIGIDITY; HYPOKINESIA; stooped posture) and HYPOTENSION. This condition is considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Pathologic features include a prominent loss of neurons in the zona compacta of the SUBSTANTIA NIGRA and PUTAMEN. (From Adams et al., Principles of Neurology, 6th ed, p1075-6)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- striating
- striation
- striatonigral atrophies
- striatonigral atrophy
- striatonigral degeneration
- Striatonigral Degenerations
- striatum
- striature
- striaturs
- striatus
- strich