STEROID 12 ALPHA HYDROXYLASE
\stˈɛɹɔ͡ɪd twˈɛlv ˈalfə hˈa͡ɪdɹəksˌɪle͡ɪs], \stˈɛɹɔɪd twˈɛlv ˈalfə hˈaɪdɹəksˌɪleɪs], \s_t_ˈɛ_ɹ_ɔɪ_d t_w_ˈɛ_l_v ˈa_l_f_ə h_ˈaɪ_d_ɹ_ə_k_s_ˌɪ_l_eɪ_s]\
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A steroid hydroxylase found in liver microsomes. It catalyzes the 12-hydroxylation of steroids in the presence of NADPH, cytochrome P-450, and molecular oxygen. It is an important enzyme in the synthesis of cholic acid from cholesterol in the liver. EC 1.14.99.-.
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