STEELE RICHARDSON OLSZEWSKI DISEASE
\stˈiːl ɹˈɪt͡ʃədsən ɒlszjˈuːskɪ dɪzˈiːz], \stˈiːl ɹˈɪtʃədsən ɒlszjˈuːskɪ dɪzˈiːz], \s_t_ˈiː_l ɹ_ˈɪ_tʃ_ə_d_s_ə_n ɒ_l_s_z_j_ˈuː_s_k_ɪ d_ɪ_z_ˈiː_z]\
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A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)
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Word of the day
tinctura quininae ammoniata
- A preparation made by dissolving quinin sulphate in alcohol [Br. Ph.].
Nearby Words
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- Steele Richardson Olszewski Disease
- steele richardson olszewski syndrome
- steeled
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